Preheat the oven to 350°F. Grease or spray a 5x9 loaf pan.Add the flour, baking powder, baking soda, salt, and cinnamon to a medium bowl and stir until thoroughly combined.
In a large bowl, beat together the butter, sugar, honey, eggs, pumpkin, banana, orange juice, and vanilla.
Stir the dry ingredients into the pumpkin/banana mixture until no streaks of flour remain.
Spoon the batter into the prepared loaf pan.
Bake the bread for 60 to 70 minutes, or until a toothpick inserted in the center of the loaf comes out clean.
Remove the bread from the oven and allow to cool in the pan for 10-15 minutes. Remove from the loaf pan. I like to run a butter knife around the edges of pan the help assure the bread will come out cleanly. Store in an airtight container.